Summary
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In 1979, space station Skylab is decommissioned through atmospheric reentry, but an oxygen tank survives and lands on Western Australia. A farmer takes it and makes a makeshift Skylab museum around it.
In 2007, biochemist Dr. Hero Martins accompanies Pentagon bioterror operatives Robert Quinn and Trini Romano to the tank. It had been sent into space carrying an infectious fungus for study, and days before the three arrived, a heavily mutated fungus escaped the tank when the farmer attempted to clean it, infecting and killing him and many men in the surrounding area. Martins takes a sample of the fungus before a patch that she stepped on corrodes the boots of her hazmat suit, infects her and starts controlling her actions. In a moment of lucidity, Martins commits suicide. The military incinerate the farm and the corpses while the sample is taken to an underground cold storage vault at the Atchison Storage Facility in Kansas.
In the intervening years, the government has sealed the vault and rented the ground level section to a self storage company. In the present day, elderly client Ma Rooney enters her storage unit intent on committing suicide, and night guards Travis and Naomi start hearing a beeping alarm and try to discover its source. It turns out to be an alert for a malfunction in the vault's systems caused by a rise in temperatures, prompting Robert to be contacted in his Raleigh, North Carolina home by a military officer who when asked for a name, nicknames herself "Abigail". Knowing the dangers brought by the fungus, which is already breaking out of the vault, Robert asks the military for transportation. Once in Kansas he is received by Trini, who drives him to pick up a device in her home.
Travis and Naomi head towards the sealed vault, where an infected rat king is outside the door separating them from a rapidly growing fungus trying to break out. Outside, Naomi's ex-boyfriend Mike arrives in his car, and a strain of the fungus that managed to get outside infecting a cockroach enters the trunk, infecting Mike's dead cat. Once Mike lets the revived cat out, it kills itself impaling its head in an antenna, spreading remains that infect both Mike and a deer. Returning to the ground level, Travis and Naomi see Mike and the deer have entered, and while the deer swells and explodes, Mike pursues them hoping to spread the fungus before the duo hides in one of the storage units. They call the military, and Abigail redirects them to Robert, who tells them that he is arriving and advises them to remain hidden.
However, manager Griffin arrives with a biker gang to take smuggled televisions from storage. Travis and Naomi leave their hiding spot wanting to warn them to flee, but Mike arrives before and infects the gang members as Griffin runs away. As he turns towards the duo, they are saved by Ma Rooney. They get outside and find Robert, who gives them a backpack nuke to be put outside the vault door to destroy the whole facility from within and eliminate any trace of the fungus. As the duo place the bomb, killing one of the infected along the way, Robert kills an escaping infected, making him fall on his back and find himself unable to get up. Griffin goes outside and tries to steal Robert's car keys when an arriving Trini kills him. Travis and Naomi then appear and get along with Robert into Trini's car, and they drive away right as the bomb explodes.
Days later, Travis is spending time with Naomi and her daughter, while Robert is in the hospital, seeing news reports praising him for preventing the outbreak while condemning the military for nearly causing it. A visiting Abigail, whose real name is Ishani, admits she leaked Robert's reports on the fungus to the press.
Source: Wikipedia (CC BY-SA 3.0)
